Question

Rank the following from highest to lowest priority according to the Cahn-Ingold-Prelog system.

A. -F
B. -H
C. -OH
D. -SH

Answer 1

The Cahn-Ingold-Prelog system ranks functional groups based on the atomic number of atoms attached to the chiral center. From highest to lowest priority, it is -OH, -SH, -F, and -H.

Step-by-step explanation:

According to the Cahn-Ingold-Prelog system, priority is assigned based on the atomic number (Z) of the atoms directly attached to the stereocenter or chiral center. The higher the atomic number, the higher the priority. In this case:

1. -OH (Oxygen has atomic number 8)
2. -SH (Sulfur has atomic number 16)
3. -F (Fluorine has atomic number 9)
4. -H (Hydrogen has atomic number 1)

Therefore, the ranking from highest to lowest priority is -OH, -SH, -F, and then -H.