Final answer:
Large observatories do not use microscopes to analyze radiation from space; instead, they use telescopes, spectrometers, and radiometers for such analyses.
Step-by-step explanation:
Large observatories employ various instruments to analyze radiation from space including telescopes, spectrometers, and radiometers. These instruments work together to gather, sort by wavelength, and record astronomical observations. Of the list provided, the item that large observatories do not use to analyze radiation from space is microscopes. Microscopes are used for magnifying small objects and are not suitable for astronomic observations, which require analyzing the light from celestial objects that are typically many light-years away.