Final answer:
Radiational cooling is most significant during the night with clear skies and low humidity because clouds can trap heat, and humid air retains heat more than dry air.
Step-by-step explanation:
The most radiational cooling occurs during the night with clear skies and low humidity. This is because clouds can act as a blanket, trapping heat and making cloudy nights generally warmer than clear ones. With clear skies, there's no such insulation, allowing heat to escape more efficiently into space. Additionally, low humidity allows for easier heat loss, as moist air tends to retain heat more effectively than dry air.