Final answer:
DNA replicates during the S phase of interphase, and errors during this process can result in mutations. These errors may lead to duplications or translocations that can affect phenotype or viability if not corrected.
Step-by-step explanation:
During DNA replication, errors can occur, leading to mutations. The phase in which DNA replicates is interphase, specifically during the S phase (Synthesis phase). This crucial phase occurs before a cell proceeds to mitosis or meiosis. Errors resulting from inaccurate DNA replication can lead to the incorporation of incorrect nucleotides, which can potentially cause mutations.
Such errors, if not repaired, can result into various forms of genetic anomalies including duplications within homologous chromosomes or translocations between nonhomologous chromosomes.
These replication errors are a natural occurrence and can happen spontaneously. However, not all replication errors will lead to a change in phenotype or be lethal; some may result in viable genetic variation.