Final answer:
During a hemolytic episode of G6PD deficiency, using Wright stain, Heinz bodies may be observed in red blood cells, indicating oxidative damage. These are distinct from the changes seen in sickle cell anemia, where red cells become crescent-shaped.
Step-by-step explanation:
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a hereditary condition that affects red blood cells and can lead to hemolytic anemia under conditions of oxidative stress. During a hemolytic episode in patients with G6PD deficiency, red cell morphology can be evaluated using a Wright stain on a blood film. The presence of Heinz bodies, which are denatured hemoglobin precipitations within red blood cells, is a characteristic finding during these episodes. These inclusions within the red cells are not seen during routine Wright stain but can be visualized using supravital staining techniques such as crystal violet or methyl violet.
Furthermore, It's important to note that conditions such as sickle cell anemia, which is characterized by red cells that take on a crescent or sickle shape as seen in various figures provided, is a different condition than G6PD deficiency. Sickle cell anemia is a result of an abnormal hemoglobin called hemoglobin S, not related to the oxidative stress-induced hemolysis seen in G6PD deficiency.