Final answer:
Autoimmune hemolytic anemia is best characterized by spherocytic red cells, where the immune system mistakenly targets and destroys its own red blood cells, leading to hemolysis.
Step-by-step explanation:
Autoimmune hemolytic anemia is best characterized by spherocytic red cells. In this condition, the body's immune system mistakenly targets and destroys its own red blood cells. The destruction of the red blood cells leads to the release of hemoglobin and activation of the complement cascade, resulting in hemolysis.