Question

The test that is most useful in differentiating Fanconi anemia from other causes of pancytopenia is:

a) Bone marrow biopsy
b) Ham acidified serum test
c) Diepoxybutane-induced chromosome breakage
d) Flow cytometric analysis of CD55 and CD59 cells

Answer 1

The test that is most useful in differentiating Fanconi anemia from other causes of pancytopenia is Diepoxybutane-induced chromosome breakage (c).

Step-by-step explanation:

The test that is most useful in differentiating Fanconi anemia from other causes of pancytopenia is Diepoxybutane-induced chromosome breakage (c). Fanconi anemia is a genetic disorder that affects the bone marrow's ability to produce blood cells. Diepoxybutane-induced chromosome breakage test measures the sensitivity of patient's cells to a chemical that produces DNA damage, which is a characteristic feature of Fanconi anemia.