Final answer:
Individuals with Swyer Syndrome, due to a mutation in the SRY gene, develop female external genitalia and have streak gonads which cause infertility. They do not develop male genitalia and lack high levels of androgens. The correct option is a) Development of male external genitalia
Step-by-step explanation:
Swyer Syndrome occurs due to a loss-of-function mutation in the SRY gene. This gene is essential for the development of male sex characteristics during embryonic development. Individuals with Swyer Syndrome typically have an XY chromosome configuration but do not develop male genitalia due to the nonfunctional SRY gene. Instead, they typically develop female external genitalia and are usually raised as females.
They have streak gonads (functionally useless remnants of what would have been testes) and thus do not develop fully male or female internal reproductive organs, leading to infertility. The lack of functional testes also results in low levels of androgens, which are male sex hormones. Therefore, they do not have high levels of androgen production like other males might.
Consequently, the correct expectation for symptoms of Swyer Syndrome would be the development of female external genitalia and streak gonads, leading to infertility. The presence of the SRY gene does occur in Swyer Syndrome since it is an XY condition, but the gene is rendered nonfunctional due to the mutation. The correct option is a) Development of male external genitalia