Final answer:
Men with Klinefelter's Syndrome are not necessarily more likely to be affected by X-linked recessive diseases due to their extra X chromosome which can mask the effects of a recessive disease gene, much like in females who typically must inherit two affected X chromosomes to express the disease.
Step-by-step explanation:
No, men with Klinefelter's Syndrome, which involves an extra X chromosome (making their pattern XXY), are not necessarily more likely to be affected by X-linked recessive diseases like hemophilia or colorblindness. In typical cases of X-linked recessive inheritance, a male only needs to inherit one affected X chromosome to express the disease because they only have one X chromosome (XY). On the other hand, females typically must inherit two affected X chromosomes to express the disease, making them less likely to be affected but more likely to be carriers if they inherit just one.
However, males with Klinefelter's Syndrome have two X chromosomes, much like females. If one of these X chromosomes carries the recessive gene for a disease like hemophilia or colorblindness, the other X chromosome can have the normal, non-mutated version of the gene, thus masking the effects of the recessive disease gene. Therefore, they are not automatically more likely to exhibit symptoms of X-linked recessive diseases, since the presence of an additional X chromosome affords them a similar genetic protection as females.