Final answer:
The false statement about neutrophils is letter c, which claims PMN count decreases during most bacterial infections, leading to leukopenia. The correct option is (c).
Step-by-step explanation:
Among the leukocytes within the human body, neutrophils play a critical role in the immune system. They are notable for their capacity to act as phagocytes, engulfing and destroying pathogens such as bacteria. Known as polymorphonuclear leukocytes (PMNs) due to their multi-lobed nucleus, these cells are equipped with granules containing potent antimicrobial substances like defensins and hydrolytic enzymes.
Given the provided statements, the incorrect one is letter c, which states that the PMN count decreases during most bacterial infections, leading to leukopenia. Contrary to this statement, during bacterial infections, one would typically observe an increase in neutrophil count, indicative of the body's response to combat the infection. This increase is known as leukocytosis. Neutrophils being plentiful components of the immune system especially during a bacterial infection where their count usually rises, not decreases.
The other statements hold true for neutrophils. They are indeed the most abundant type of leukocyte. An upsurge in the count of these cells is referred to as leukocytosis and signals an active response to infection. Their distinctive multi-lobed nucleus and the presence of granules such as defensins and hydrolytic enzymes contribute to their powerful mechanism in fighting infections.