Question

Arrange the following steps in the blood clotting process in the correct sequence:

1) Formation of prothrombinase
2) Conversion of prothrombin to thrombin
3) Conversion of fibrinogen to fibrin

a. 3, 2, 1
b. 2, 3, 1
c. 1, 2, 3
d. 3, 1, 2

Answer 1

The correct sequence for the steps in the blood clotting process is formation of prothrombinase, conversion of prothrombin to thrombin, and conversion of fibrinogen to fibrin, which corresponds to 1, 2, 3.

Step-by-step explanation:

The correct sequence in the blood clotting process is as follows:

1. Formation of prothrombinase.
2. Conversion of prothrombin to thrombin.
3. Conversion of fibrinogen to fibrin.

When a blood vessel is injured, the clotting process, also known as coagulation, begins with the formation of a platelet plug, followed by the coagulation cascade. The cascade can be initiated via two pathways: the intrinsic or extrinsic pathway, which then converge into the common pathway. In the common pathway, prothrombinase acts on prothrombin (factor II), converting it into its active form thrombin. Thrombin then catalyzes the conversion of fibrinogen (factor I), a soluble protein, into fibrin, an insoluble protein that forms the clot's structure. Throughout this process, other factors such as factor XIII help to stabilize the clot, ensuring it remains intact to prevent further bleeding.