Final answer:
The false statement is that John Doe with type O- blood can safely receive either type O or type AB blood. He can only receive type O- blood due to his naturally occurring anti-A and anti-B antibodies.
Step-by-step explanation:
The false statement about John Doe, who has type O- blood, is that he can safely receive either type O or type AB blood. In fact, an individual with type O- blood can only receive type O- blood. This is because type O- blood contains both anti-A and anti-B antibodies, which will attack any transfused blood that has A or B antigens present on the red blood cells (RBCs). As for the other statements: John Doe indeed has neither A nor B antigen on his RBCs (true), and he naturally has both A & B antibodies (true).
Lastly, John Doe is considered a universal donor because his blood can be given to individuals with any blood type as it lacks A or B antigens, which could otherwise elicit an immune response.