Final answer:
The genome of Otzi the Ice Man most closely resembles that of b) Neanderthals, suggesting interbreeding between them and early modern humans.
Step-by-step explanation:
Otzi the Ice Man's genome most closely resembles that of Neanderthals.
Studies have shown that there was interbreeding between Neanderthals and early modern humans, and the Neanderthal genome has about 2 to 3 per cent greater similarity to people living outside Africa than to people in Africa. This suggests that some genetic exchange took place between Neanderthals and modern humans as they emerged out of Africa. Therefore, the genome of Otzi the Ice Man, who lived in Europe, shows a closer resemblance to Neanderthals.