Question

Neurons in the central nervous system have less chance of regenerating for all of the following reasons except?

1) Lack of neurotrophic factors
2) Inhibitory environment
3) Presence of glial scars
4) High regenerative capacity

Answer 1

The neurons in the CNS have a reduced chance of regenerating mostly due to lack of neurotrophic factors, an inhibitory environment, and glial scars. A 'high regenerative capacity' is not a reason for this reduced chance of regeneration but rather, it is a factor missing in CNS neurons.

Step-by-step explanation:

Neurons in the central nervous system (CNS) have less chance of regenerating due to several reasons. These include the lack of neurotrophic factors which are needed for the growth and survival of neurons, an inhibitory environment that can prevent axon growth, and the presence of glial scars which form as a result of injury and create a physical and chemical environment that is hostile to neural regeneration. However, these factors do not include neurons having a high regenerative capacity. In fact, CNS neurons have a low inherent capacity for regeneration, which is why damage to the brain or spinal cord leads to lasting deficits, unlike the peripheral nervous system (PNS) that has a greater capacity for repair.