Final answer:
Nicotine is the agent that creates psychological dependence on tobacco products.
Step-by-step explanation:
Nicotine is the agent that creates psychological dependence on tobacco products. Nicotine is the active chemical constituent in tobacco and is responsible for the addictive effects of smoking. When nicotine is inhaled or ingested, it interacts with acetylcholine receptors in the brain, resulting in addictive and dependence-forming behaviors.