Final answer:
The granulosa cells do not secrete a substance that forms the zona pellucida.
he granulosa cells do not secrete androgen-binding protein, which is actually a function of the Sertoli cells in the testes.
Step-by-step explanation:
The granulosa cells have several important functions in the ovarian follicle, but one of the functions listed is NOT performed by them:
- Secretion of inhibin: Granulosa cells produce inhibin, which suppresses the release of follicle-stimulating hormone (FSH) from the pituitary gland.
- Secretion of estrogens: Granulosa cells work with the theca cells to produce estrogens, such as estradiol, which play a crucial role in the development and regulation of the female reproductive system.
- Secretion of a substance that forms the zona pellucida: This function is not performed by granulosa cells. The zona pellucida is actually secreted by the primary oocyte itself.
- Secretion of androgen-binding protein: Granulosa cells produce androgen-binding protein, which helps to regulate the availability of androgens in the follicle.
- Secretion of paracrines that support follicle development: Granulosa cells produce paracrine factors that support the development and maturation of the follicle.
The granulosa cells do not secrete androgen-binding protein, which is actually a function of the Sertoli cells in the testes. Granulosa cells are involved in the secretion of inhibin, estrogens, constituents of the zona pellucida, and paracrine factors that aid in follicle development.
The function of granulosa cells that is NOT listed correctly in the options provided is the secretion of androgen-binding protein. Granulosa cells are known for their roles in fertility and reproductive health, including the secretion of inhibin, secretion of estrogens, contributing to the formation of the zona pellucida, and secretion of paracrines that support follicle development. However, the secretion of androgen-binding protein is primarily the function of Sertoli cells in the testes, not of granulosa cells in ovarian follicles.
Granulosa cells play a pivotal role in folliculogenesis and the ovarian cycle. They proliferate as the primary follicles develop into secondary follicles, contribute to the production of estrogens in concert with theca cells, and support the oocyte surrounded by the zona pellucida. Additionally, the granulosa cells undergo luteinization after ovulation, transforming into the corpus luteum which produces progesterone, an essential hormone for the maintenance of pregnancy.