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Which of the sequences could form a hairpin?

1) ATTATTGGCGCTAACGCCAATTTT
2) CGCCAAAAAATCGCCCCCCAATTA
3) GCCGCCGCCGCCCCATTATTATTAT
4) TTCAATAATCGCTAATAACTGA
5) ATTATTTCGTACCCCCAATTTT

1 Answer

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Final answer:

Sequence 1) ATTATTGGCGCTAACGCCAATTTT could form a hairpin since it contains an inverted repeat where the first half is complementary to the second half. This allows for the formation of a hairpin structure as complementary bases within the strand can pair with each other. The correct sequence that could form a hairpin is sequence 1) ATTATTGGCGCTAACGCCAATTTT

Step-by-step explanation:

To determine which of the sequences could form a hairpin, we need to identify sequences that have the potential for intra-chain base pairing, meaning that there are complementary bases within the same strand that can pair with each other to form the structure. In DNA, adenine (A) pairs with thymine (T) and cytosine (C) pairs with guanine (G).

Looking at the sequences given in the question, sequence 3) GCCGCCGCCGCCCCATTATTATTAT does not have a clear palindromic pattern that would allow for hairpin formation as its bases do not suggest an intra-strand complementary pairing.

Comparing to known principles of DNA complementary base pairing, we can further analyze the sequences. For a hairpin to form, there must be a series of nucleotides that are inversely complementary within the sequence. For instance, if a sequence had a segment like 5'-AATT-3' at one end and 3'-TTAA-5' at the other (or in an internal section), these would base pair with each other and could potentially form a hairpin.

Therefore, the correct sequence that could form a hairpin is sequence 1) ATTATTGGCGCTAACGCCAATTTT since it contains an inverted repeat where the first half is complementary to the second half. This allows the formation of a hairpin as the ATTATT sequence at the 5' end can base pair with the AATTTT sequence at the 3' end.

User Michael Hahsler
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