Final answer:
The nurse's first response should be to apply manual pressure to the site. This can help slow down or stop the bleeding.
Step-by-step explanation:
The nurse's first response should be to apply manual pressure to the site. Applying direct manual pressure to the insertion site can help slow down or stop the bleeding. This can be done by using a sterile gauze pad or cloth and applying firm pressure to the area for several minutes until the bleeding stops or slows down.