Question

In any case, the CAAT box, along with the GC box may ________.

1) direct the RNA polymerase II so that it is facing in the proper orientation for transcription
2) bind transcription factor proteins that enhance transcription
3) bind HDACs to regulate transcription via histone slippage
4) A and B
5) all of the above

Answer 1

The CAAT and GC boxes within eukaryotic promoters bind transcription factors, directing RNA polymerase II and enhancing transcription. They do not, however, bind HDACs for histone slippage regulation.

Step-by-step explanation:

The CAAT box and GC box are important elements in the regulation of gene transcription. These sequences are essential for the binding of transcription factors. The CAAT box, with the consensus sequence 5'-CCAAT-3', and the GC box, with the consensus sequence 5'-GGGCGG-3', both function as promoter-proximal elements. They have distinct roles in transcriptional regulation:

• Directing RNA polymerase II so that it is facing in the proper orientation for transcription.
• Binding transcription factor proteins that enhance transcription.

While they do not bind HDACs to regulate transcription via histone slippage, the CAAT and GC boxes are important for the initiation and regulation of transcription in eukaryotic cells.