Question

Silencers bind repressors that inhibit transcription if necessary. These proteins inhibit DNA polymerase from binding to RNA polymerase II. True or False?

Answer 1

Silencers bind repressors to inhibit transcription by impeding RNA polymerase, not DNA polymerase. Repressors and activators play essential roles in regulating transcription efficiency, with enhancers aiding in promoting transcription.

Step-by-step explanation:

False. Silencers bind repressors that inhibit transcription, but these proteins do not inhibit DNA polymerase; rather, they impede the progress of RNA polymerase along the DNA strand, preventing transcription to mRNA. Repressors bind to non-coding sequences on DNA that are close to or overlap the promoter region. Occasionally, these repressor proteins may dissociate from the operator, allowing transcription to proceed. Similarly, activator proteins enhance the interaction between RNA polymerase and a particular promoter, helping facilitate the transcription process. Enhancers work alongside activators by bending DNA to facilitate their interaction with the transcription initiation complex, promoting the initiation of transcription by RNA polymerase II.