Final answer:
The location of the nucleus does not determine the site of cleavage during cytokinesis, as this is influenced by the mitotic spindle and in plant cells, by vesicles from the Golgi apparatus.
Step-by-step explanation:
The statement 'The location of the nucleus determines the site of cleavage during cytokinesis' is false. The site of cleavage during cytokinesis in animal cells is often determined by the position of the mitotic spindle and not specifically the location of the nucleus. The spindle apparatus is responsible for the equal segregation of chromosomes during cell division, and it also determines the plane of cell division. This eventually leads to the formation of the cleavage furrow, which is where the cell membrane will pinch inward to eventually divide the cytoplasm into two separate daughter cells. In plant cells, a cell plate forms along the line of division, eventually becoming the new cell wall, and this process is directed by vesicles from the Golgi apparatus that gather at the metaphase plate, not by the location of the nucleus itself.