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Explain why Aquaporins cannot conduct protons?

User Pifor
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Final answer:

Aquaporins are highly selective channels that facilitate water transport across cell membranes without letting protons pass due to the small pore size and positive charges within the channel, which prevent electrolytes from leaking. Their selective permeability is crucial for maintaining cellular homeostasis.

Step-by-step explanation:

Aquaporins are specialized channel proteins that facilitate the rapid transport of water across the cell membrane. They feature a very narrow pore that is just wide enough to allow single water molecules to pass through in a single file but is too small for protons (hydrogen ions) or other ions to pass, thanks to their larger size or charge. This is an example of selective permeability, which is central to a cell's ability to maintain homeostasis.

Moreover, the inside of the aquaporin channel typically has positive charges, which serve to repel the passage of protons, thus preventing electrolytes from leaking across the cell membrane. This phenomenon is known as electrochemical exclusion. Such specificity ensures that aquaporins effectively conduct water molecules without letting protons disrupt the delicate balance of electrolytes and pH within the cell.

Under flooding conditions, plant cells may require more water uptake, hence aquaporins facilitate this process, while during droughts, they prevent excessive water loss. The gating of aquaporins by low and high pH allows plants to regulate water movement, aiding in homeostasis and stress response, which can be critical for survival in varying environmental conditions.

User TCCV
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