Question

What is responsible for adding sugars to dolichol phosphate?

1) membrane-bound glycosyltransferases
2) membrane-bound oligosaccharyltransferase
3) membrane-bound gangliosidase
4) glycosylsynthetase
5) peptidyltransferase

Answer 1

Membrane-bound glycosyltransferases are responsible for adding sugars to dolichol phosphate in the process of glycoprotein synthesis.

Step-by-step explanation:

The main enzyme responsible for adding sugars to dolichol phosphate is membrane-bound glycosyltransferases. These enzymes are involved in the process of glycoprotein synthesis, where they attach terminal sugars to the core glycoside of proteins as they travel through the Golgi vesicles of the endomembrane system. When these vesicles fuse with the plasma membrane, the sugars end up on the exterior cell surface.