Final answer:
The printing press did not involve religious persecution during the Renaissance. It played a significant role in the spread of new knowledge and the Protestant Reformation.
Step-by-step explanation:
The correct answer is A. Controversies over the use of the printing press.
The controversies over the use of the printing press during the Renaissance did not involve religious persecution. The printing press was a tool that allowed for the spread of new knowledge, including religious ideas. The use of the printing press actually played a significant role in the Protestant Reformation, as it allowed Martin Luther and other reformers to spread their criticisms of the Catholic Church and their calls for religious reform. While the printing press played a central role in spreading Reformation ideas, it was not in itself an act of religious persecution. In contrast, Calvin's Geneva was known for its strict religious rules; the treatment of Anabaptists involved persecution due to their religious beliefs; and the Spanish Inquisition was notorious for its persecution of those considered heretics by the Catholic Church.