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ACTH is a tropic hormone that stimulates cortisol release.
1) True
2) False

1 Answer

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Final answer:

The statement that ACTH is a tropic hormone stimulating cortisol release from the adrenal cortex is true. ACTH, triggered by CRH from the hypothalamus, facilitates the production of corticosteroids, such as cortisol, which play a key role in the body's response to stress and immune regulation.

Step-by-step explanation:

1) True. The adrenocorticotropic hormone (ACTH) does stimulate the release of cortisol from the adrenal cortex.

Adrenocorticotropic hormone, or ACTH, is a hormone produced by the anterior pituitary gland that plays a crucial role in regulating the stress response and maintaining homeostasis in the body through its effects on the adrenal cortex. ACTH stimulates the adrenal cortex to secrete corticosteroid hormones, notably glucocorticoids such as cortisol, which have several important functions, including the regulation of metabolism and immune response.

The production of ACTH is initiated by the corticotropin-releasing hormone (CRH) from the hypothalamus in response to physiological rhythms and stress. Cortisol itself then provides a negative feedback to the hypothalamus and pituitary to regulate the production of CRH and ACTH, ensuring the balance of hormone levels. At the cellular level, cortisol influences the transcription of certain genes, changes enzyme concentrations, and affects overall cellular metabolism, highlighting its multiplicative impact across numerous systems in the body.

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