Question

M cyclin concentrations rise as the cell begins to enter _____ and the concentrations peak at _____. Cell changes in the cell cycle, like the assembly of mitotic spindles and alignment of sister chromatids along the spindles, are induced by M cyclin-Cdk complexes. The destruction of M cyclins during _____ and _____, after the spindle assembly checkpoint is satisfied, causes the exit of _____ and _____.

Answer 1

M cyclin levels rise initiating prophase and peak during metaphase, triggering important mitotic activities. The subsequent degradation of M cyclins at anaphase and telophase facilitates the transition from mitosis to cytokinesis.

Step-by-step explanation:

M cyclin concentrations rise as the cell begins to enter prophase and the concentrations peak at metaphase. Cell changes in the cell cycle, like the assembly of mitotic spindles and alignment of sister chromatids along the spindles, are induced by M cyclin-Cdk complexes. The destruction of M cyclins during anaphase and telophase, after the spindle assembly checkpoint is satisfied, causes the exit of mitosis and entry into cytokinesis.

Cyclins regulate the progress of the cell through the various checkpoints of the cell cycle. M cyclin partnered with Cdk (cyclin-dependent kinase) forms a complex that is crucial for a cell to pass the metaphase (M) checkpoint. As a cell approaches mitosis, M cyclin levels increase, peaking at mitosis to enable important cell cycle activities. Afterward, M cyclins are degraded, which allows the cell to exit mitosis. This degradation ensures that the cell completes mitosis and proceeds to cytokinesis, and ultimately prepares for the next cell cycle phase.