Final answer:
A histone octamer is comprised of eight histone proteins. The DNA wraps tightly around the histone core, forming a nucleosome.
Step-by-step explanation:
A histone octamer is comprised of eight histone proteins. The histone proteins are basic proteins rich in lysine and arginine amino acids. They bind to the negatively charged phosphodiester backbone of DNA. The DNA wraps tightly around the histone core, forming a nucleosome. A nucleosome is comprised of a core of eight histone proteins and about 146 base pairs of DNA wrapped around it.