Final answer:
If the amount of solute excreted per minute is greater than the filtered load, the net effect on the solute is secretion into the renal tubules.
Step-by-step explanation:
The correct answer is option 4) secretion into the renal tubules.
If the amount of solute excreted per minute is greater than the filtered load, it means that more solute is being excreted from the body than what was originally filtered by the kidneys. This can happen when the body needs to eliminate excess solutes or toxins.
In the renal tubules, substances can be reabsorbed back into the blood or secreted into the tubules. In this case, when the amount of solute excreted is greater than the filtered load, it indicates an increase in secretion of solute into the renal tubules.