90.7k views
0 votes
While phages are capable of having linear and circular genomes, they usually have what form?

1) Linear form
2) Circular form
3) Both linear and circular forms
4) Cannot be determined

User PikkuKatja
by
6.9k points

1 Answer

2 votes

Final answer:

Most bacteriophages tend to have circular genomes, especially when their DNA is packed within the virus particle, to accommodate the large length of DNA in a small space. Thus, while phages can have both linear and circular forms, the usually adopted form after packaging is circular.

Step-by-step explanation:

Phages, or bacteriophages, are viruses that infect bacteria and have fascinating life cycles, which can be broadly categorized into the lytic and lysogenic cycles. During the lytic cycle, phages replicate within the host cell and eventually cause the cell to lyse, releasing the new phages. In contrast, the lysogenic cycle involves the integration of the phage DNA into the bacterial host's genome, where it can remain dormant for extended periods as a prophage until certain environmental triggers initiate its excision and entry into the lytic cycle.

When considering the physical form of phage genomes, it becomes apparent that, while phages are capable of having both linear and circular genomes, a significant adaptation for these viral entities is the circularization of their DNA. The packaging of viral DNA within the phage particle often results in a circular form due to the covalent linkage of DNA ends, conferring the shape of an endless belt. This aspect is crucial because the contour length of their DNA is usually much greater than the dimensions of the viral particle, requiring an efficient packaging strategy. For example, some single-stranded DNA phages, such as 6X174, become double stranded and circular to fit within their capsid.

In summary, while there is variation among phage species, most phages tend to have circular genomes once they are packed within the virus particle—a necessity due to the constraints of packaging lengthy DNA into the relatively small phage head. Therefore, the correct option answer would generally be 2) Circular form, although this characterization could vary depending on the specific type of phage being considered.

User Rolnn
by
7.1k points