Question

Up-regulation of receptors results in?

1) increased sensitivity to its ligand
2) decreased sensitivity to its ligand
3) occurs when a ligand has been present at high levels
4) both B and C

Answer 1

Up-regulation of receptors leads to increased sensitivity to the ligand, allowing for a greater cellular response due to an increased number of receptors available for ligand binding.

Step-by-step explanation:

Up-regulation of receptors typically results in increased sensitivity to its ligand. This cellular mechanism occurs as the number of receptors on the cell surface increases in response to a lower level of the hormone, allowing the cell to respond more actively to a particular hormone or ligand.

This enhancement in cellular activity indicates a greater likelihood that the ligands will bind to the receptors, thus increasing the chances of a cellular response.