Question

The human genome is 3×10⁹ bp in length. Calculate how many fragments would result from the complete digestion of the human genome with specific enzymes?

1) 1.15×10⁷
2) 1.97×10⁴
3) 7.32×10⁵
4) 5.81×10⁵
5) 8.69×10⁵

Answer 1

The complete digestion of the human genome by specific enzymes results in around 700,000 fragments, which corresponds to 7.32×10⁵ fragments upon complete digestion.

Step-by-step explanation:

The question seeks to calculate the number of fragments that would result from the complete digestion of the human genome using specific enzymes. This calculation requires understanding that the human genome comprises approximately 3 billion base pairs (bp), and digestion by specific enzymes would cut this genomic sequence into pieces.

It has been established that the complete digestion of the human genomic DNA with restriction endonucleases tends to result in a specific number of fragments that can be used to create a genomic library. Genomic libraries contain all genes of an organism, which allow for the isolation of commercially important genes. For humans, the complete genomic DNA is cleaved into about 700,000 (7 x 105) pieces by these enzymes.

Therefore, based on this knowledge, theto how many fragments would result from the complete digestion of the human genome with specific enzymes is 7.32×105.