Question

Which of the following is the most frequent cause of DNA damage?

1) mistaken base addition during DNA replication
2) Depurination due to thermal fluctuations
3) Spontaneous demination of cystosine or adenine
4) Pyrimidine dimer formation from UV-exposure

Answer 1

Pyrimidine dimer formation from UV-exposure is the most frequent cause of DNA damage.

Step-by-step explanation:

The most frequent cause of DNA damage is Pyrimidine dimer formation from UV-exposure. When DNA is exposed to UV radiation, adjacent pyrimidines, typically thymines, can dimerize, leading to a structural change in the DNA strand. This dimerization can cause mutations and structural abnormalities in the DNA sequence.