Question

Which of the following would NOT be involved in the synthesis of a tRNA molecule?

1) RNA polymerase
2) Aminoacyl synthetase
3) Termination DNA sequence
4) Promoter DNA sequence
5) Ribonucleoside triphosphates
6) snRNP

Answer 1

snRNP would NOT be involved in the synthesis of a tRNA molecule. snRNPs are primarily involved in splicing of pre-mRNA, whereas components like RNA polymerase, promoter and termination sequences, and ribonucleoside triphosphates play direct roles in tRNA synthesis.

Step-by-step explanation:

snRNP (small nuclear ribonucleoproteins) would NOT be involved in the synthesis of a tRNA molecule.

In the process of tRNA synthesis, several components are involved:

• RNA polymerase is responsible for transcribing the tRNA gene into tRNA.
• A termination DNA sequence is necessary to signal the end of transcription.
• A promoter DNA sequence is crucial for the initiation of transcription.
• Ribonucleoside triphosphates are the building blocks that are added to form the RNA molecule.

However, snRNPs are primarily involved in splicing of pre-mRNA and not involved in the tRNA synthesis. Aminoacyl synthetase functions not during the transcription of tRNA but rather during translation, specifically linking tRNAs with their appropriate amino acids.

Transcription of tRNA occurs in the nucleus of eukaryotic cells where genomic DNA resides. In contrast, translation happens at the ribosomes in the cytoplasm, where the tRNA contributes its amino acid to the growing polypeptide chain during protein synthesis. While synthesize, tRNA undergoes specific post-transcriptional modifications before becoming functional in translation.