Question

While most IgSF members are involved in various aspects of immune function, some of them mediate ____cell-cell adhesion?

Answer 1

Some members of the Immunoglobulin Superfamily (IgSF) such as selectins and NCAMs mediate cell-cell adhesion, contributing to processes like blood clotting and neural connections.

Step-by-step explanation:

Some members of the Immunoglobulin Superfamily (IgSF) mediate cell-cell adhesion. For example, Intercellular Cell Adhesion Molecules (ICAMs) such as selectins and NCAMs play a role in binding cells together. Selectins are involved in blood clotting and recognize specific receptors on other platelets, contributing to clot formation. NCAMs enable neural connections in the brain.