Final answer:
A cell that fails at the G1 to S checkpoint is likely 2) to enter the G0 phase and exit the cell cycle.
Step-by-step explanation:
A cell that fails at the G1 to S checkpoint, also known as the restriction point, typically does not meet the requirements for cell division to proceed. This checkpoint assesses factors like cell size, reserves, and genomic DNA damage. If the cell fails at this checkpoint, it can either halt the cell cycle and attempt to remedy the problematic condition, or it can enter the G0 phase, where it exits the cell cycle and awaits further signals when conditions improve. Therefore, the correct answer is 2) Enter the G0 phase and exit the cell cycle.