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For a given signal (e.g. acetylcholine), is it reasonable to expect that different cells that can detect the specific signal will respond in different ways? In other words, can a specific signal/receptor pair have different effects in different cell types?

User Mark Bao
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Final answer:

Different cells can respond uniquely to the same signal/receptor pair due to differences in protein expression and signaling components. Signal integration and cellular functionalities further influence these variations, reinforcing the specificity of responses in multicellular organisms.

Step-by-step explanation:

Each cell is unique in its composition and function, and therefore responds uniquely to various signals such as acetylcholine. The interaction between a signaling molecule and its receptor can trigger a range of potential signal transduction pathways. This variation primarily stems from the fact that different types of cells express different proteins and receptors. Even when cells contain the same type of receptors, these may interact with different associated signaling components, leading to diverse cellular responses. Additionally, the complexity of signal integration means that multiple signals can converge to dictate the specific response of a cell. These intricate biological processes contribute to the fulfillment of multiple cellular requirements before a specific action is undertaken.

Understanding the relationship between ligand structures and their mechanisms of action is crucial in identifying how similar ligands can activate different receptors or the same receptor to produce varied effects. When discussing neurotransmitters such as acetylcholine, we observe that while some neurotransmitter effects may be consistent across different cells, others can stimulate, inhibit, or moderately affect various target cells, defining the uniqueness of cellular responses within multicellular organisms.

User Faria
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