Final Answer:
Cytokine(s) is not secreted by TH₂ cells that are IFN-gamma and lymphotoxin (LT) thus option 1 is correct.
Step-by-step explanation:
TH₂ cells, or T helper 2 cells, primarily secrete interleukin-4 (IL-4), interleukin-5 (IL-5), interleukin-10 (IL-10), and transforming growth factor-beta (TGF-beta). Therefore, option 1, which includes interferon-gamma (IFN-gamma) and lymphotoxin (LT), is correct. IFN-gamma is typically associated with TH₁ cells, not TH₂ cells. LT, also known as tumor necrosis factor-beta (TNF-beta), is produced by various immune cells, but its secretion is not a characteristic function of TH₂ cells.
Understanding the specific cytokines associated with different T helper cell subsets is crucial in comprehending the immune response. TH₂ cells play a significant role in allergic and parasitic responses by releasing IL-4, IL-5, IL-10, and TGF-beta. Each cytokine has distinct functions, contributing to the regulation of immune reactions and the coordination of various immune cells.
In summary, TH₂ cells do not secrete IFN-gamma and lymphotoxin (LT), making option 1 the correct choice.