Question

All of the following indicate correct intermolecular associations except _____?

1) Janus kinases (JAKs): serglycin
2) L-selectin: GlyCAM-1
3) VLA-4: VCAM-1
4) JAKs: signal transducers and activators of transcription (STATs)
5) CD40: CD40 ligand

Answer 1

The pairings VLA-4: VCAM-1 and CD40: CD40 ligand represent correct intermolecular associations important for immune system communications between cells. These are involved in the function of white blood cells and antigen-presenting cells, respectively.

Step-by-step explanation:

All of the following indicate correct intermolecular associations except for one particular pairing that is not correctly matched in the context of cellular adhesion molecules. The pair VLA-4: VCAM-1 is a correct association since VLA-4 (Very Late Antigen-4) is an integrin found on the surface of many cell types and VCAM-1 (Vascular Cell Adhesion Molecule-1) is a protein expressed by endothelial cells. They interact specifically during the immune response to allow white blood cells to move out of the bloodstream into tissues.

The pairing of CD40: CD40 ligand (CD40L) is another correct association. CD40 is a costimulatory protein found on antigen-presenting cells and is required for their activation. The CD40 ligand is expressed on the surface of T cells and binds to CD40, leading to a variety of immune responses.

Since both of these are correct associations, the question may be incomplete or missing the incorrect pairing. Take note that ICAMs, NCAMs, VLA-4, VCAM-1, and the CD40: CD40 ligand pairing are all important components of the immune system's cellular interactions.