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Besides increasing the conduction rate, how else does mylenation help?

User Mhvelplund
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Final answer:

Myelination increases conduction rate and signal strength, and it also conserves energy by reducing the need for voltage-gated Na+ and K+ channels along the entire length of the axon. In diseases such as multiple sclerosis where myelination is damaged, action potential propagation is less efficient due to increased current leak. The nodes of Ranvier facilitate saltatory conduction, enabling the action potential to 'jump' and travel quickly and efficiently.

Step-by-step explanation:

Besides increasing the conduction rate, myelination provides several other benefits to neuronal function. The presence of a myelin sheath around an axon enhances signal strength and efficiency in several ways aside from just speed. The myelin acts as an insulator, which reduces the likelihood of electrical current leaking out of the axon. This insulation ensures that the action potential can travel along the axon more swiftly and with less degradation of the signal.

In diseases like multiple sclerosis, where myelination is compromised, we see a reduction in the efficiency of action potential propagation due to the increased likelihood of current leak. Furthermore, the myelin sheath gives rise to the nodes of Ranvier, which are small gaps in the myelin sheath where voltage-gated Na+ and K+ channels are concentrated. The action potential 'jumps' from one node to the next, in a process called saltatory conduction, which is much faster than if the action potential had to travel continuously along the entire length of the axon.

Finally, having voltage-gated channels concentrated at the nodes of Ranvier also means that the neuron uses less energy. It doesn't need to maintain these channels along the entire length of the axon, only at the nodes. This way, myelination not only speeds up signal transmission but also makes it more energy-efficient. The saltatory conduction and energy savings are crucial for maintaining fast and efficient neural communication.

User Astrochun
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