Final answer:
ALS patients have elevated levels of calcium, which is a central factor in this neurodegenerative disorder. Calcium-permeable AMPA receptors and glutamate excitotoxicity are believed to contribute to disease progression.
Step-by-step explanation:
The research shows that ALS patients have elevated levels of calcium. Calcium dysregulation is a central factor in the neurodegenerative disorder ALS (Amyotrophic Lateral Sclerosis). This disorder results in muscle atrophy, paralysis, and eventual death of patients. Calcium-permeable AMPA receptors and glutamate excitotoxicity are believed to play crucial roles in ALS progression.