Question

Red blood cells have been very useful in the study of membrane proteins and the protein components that provide structural support. Which of the following is the principal fibrous protein in the cortex of RBCs?

1) Actin
2) Spectrin
3) Myosin
4) Keratin

Answer 1

Spectrin is the principal fibrous protein in the cortex of red blood cells, forming a mesh that provides shape and flexibility to the cells. The correct option is 2.

Step-by-step explanation:

The principal fibrous protein in the cortex of red blood cells (RBCs) is spectrin. Spectrin forms a mesh-like structure that gives the cell its shape and maintains its flexibility, allowing it to deform as it moves through capillaries. This structural protein is essential for the proper function of RBCs, and it is linked to the plasma membrane by various other proteins. While actin also plays a role, spectrin is the major component of the supportive network.