Final answer:
Monocytes and neutrophils are the first responders to the injury caused by ischemia. Neutrophils arrive at the site of inflammation first and engulf and digest pathogens. Monocytes then differentiate into macrophages and continue the process of phagocytosis.
Step-by-step explanation:
The first responders to the injury caused by ischemia are monocytes and neutrophils. When there is an injury or infection, neutrophils are the first type of white blood cells to arrive at the site of inflammation. They are phagocytic cells that engulf and digest pathogens. Monocytes then follow and differentiate into macrophages, which continue the process of phagocytosis and help in the resolution of the inflamed site.