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ORF2 in Lines acts in reverse transcriptase activity as well as endonuclease activity?

User Aultimus
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Final answer:

ORF2 in LINES acts as a reverse transcriptase and also has endonuclease activity. The reverse transcriptase activity generates a complementary DNA copy of the transposable element, and the endonuclease activity degrades the RNA template after reverse transcription.

Step-by-step explanation:

ORF2 in LINES acts as a reverse transcriptase and also has endonuclease activity. The reverse transcriptase activity of ORF2 allows it to generate a complementary DNA (cDNA) copy of the transposable element.

This process involves the use of a tRNA molecule as a primer for the synthesis of the first strand of cDNA. The endonuclease activity of ORF2, specifically the RNAse H activity, degrades the RNA template after reverse transcription.

User Dinistro
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