Final answer:
The correct answer is 1). The cytosol occupies the largest volume within a human cell such as a hepatocyte, as it is the fluid part that contains organelles and is the medium for metabolic reactions.
Step-by-step explanation:
When considering the volume occupied by different compartments within a human cell such as a hepatocyte, the cytosol (option 1) typically occupies the largest volume. The cytosol is the fluid part of the cytoplasm and it houses the cell's organelles and provides a medium for metabolic reactions. In comparison, the nucleus occupies a substantial volume as well but is generally smaller than the cytosol. The endoplasmic reticulum (ER) also has a significant volume due to its extensive membrane network within the cell. However, it would not exceed the cytosol in terms of total volume. Mitochondria are numerous in cells such as hepatocytes, but collectively their volume is less than that of the cytosol or nucleus. Peroxisomes are much smaller than other organelles and occupy a much smaller volume in the cell.