Final answer:
Phosphorylation of POL II's C terminus is achieved through kinase activity that adds phosphate groups using ATP, enabling the initiation of mRNA synthesis.
Step-by-step explanation:
Phosphorylation of POL II's C terminus occurs through the addition of phosphate groups to the aminoterminus of the RNA polymerase by a kinase. This process is a post-translational modification and is catalyzed by protein kinases using ATP as the substrate. The addition of phosphate groups can activate or turn off the function of the protein.
After phosphorylation, some transcription factors dissociate from the complex, preparing POL II to begin synthesizing mRNA.
Phosphorylation of POL II's C terminus occurs through the addition of phosphate groups to the aminoterminus of the RNA polymerase by a kinase.
This process is a post-translational modification and is catalyzed by protein kinases using ATP as the substrate. The addition of phosphate groups can activate or turn off the function of the protein.