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Can Na/K ATPase repolarize the cell alone?
1) Yes
2) No

1 Answer

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Final answer:

The Na/K ATPase plays a key role in maintaining the electrochemical gradient, but cannot repolarize the cell alone as K+ channel activity is also needed for this process.

Step-by-step explanation:

No, the Na/K ATPase alone cannot completely repolarize a cell as it requires the cooperative action of other ion channels to restore the resting potential.

The Na/K ATPase (sodium-potassium pump) is crucial for maintaining the electrochemical gradient across the cell membrane by actively transporting 3 Na+ ions out of the cell and 2 K+ ions into the cell against their concentration gradients, using ATP. This activity contributes to a negative resting membrane potential due to the net transfer of one positive charge out of the cell. However, during an action potential, Na+ channels open and allow Na+ ions to enter the cell, resulting in depolarization.

Subsequently, K+ channels open, allowing K+ ions to exit the cell, leading to repolarization. While the Na/K ATPase helps restore ion concentrations after multiple action potentials, it is the opening of K+ channels that primarily drives repolarization. The Na/K ATPase alone is not sufficient to repolarize the cell immediately following an action potential because the timing and duration of K+ channels opening are also necessary to re-establish the resting membrane potential.

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