Final answer:
False. During DNA replication, RNA primers used for initiation must be removed and replaced with DNA nucleotides. DNA replication involves removing RNA primers from Okazaki fragments and replacing them with DNA nucleotides for completion and accuracy.
Step-by-step explanation:
False. To complete DNA replication, the RNA primers used for initiation must be removed and replaced with DNA. During replication, the leading strand is synthesized continuously, while the lagging strand is synthesized discontinuously in short fragments called Okazaki fragments. These fragments require RNA primers to start synthesis, and the RNA primers are later removed and replaced with DNA nucleotides.
Indeed, DNA replication involves the intricate process of synthesizing both leading and lagging strands, each with distinct mechanisms. The leading strand undergoes continuous synthesis in the 5' to 3' direction, obviating the need for repeated priming. Conversely, the lagging strand encounters a unique challenge, necessitating the creation of Okazaki fragments due to its 3' to 5' orientation. RNA primers are vital for initiating each Okazaki fragment.
Post-synthesis, these RNA primers become obsolete and must be excised and replaced with DNA nucleotides. This critical step ensures the seamless transition from RNA- to DNA-containing fragments, culminating in a fully functional and accurate DNA replication process.