Question

Laminins are a family of extracellular glycoproteins, which contain binding sites to:

1) other components of the extracellular matrix
2) cell-surface receptors
3) cytoplasmic receptors
4) transcription factors
5) ribosomes

Answer 1

Laminins are extracellular glycoproteins that bind to other ECM components and cell surface receptors, facilitating cell adhesion, migration, and signaling. The correct option is 2) cell-surface receptors

Step-by-step explanation:

Laminins are a family of extracellular glycoproteins that play a critical role in the structure and function of the extracellular matrix (ECM). They are integral to the basal lamina, a part of the ECM, facilitating cell adhesion, differentiation, migration, and cell signaling. Laminins contain binding sites for several components that include:

• Other components of the extracellular matrix (ECM)
• Cell-surface receptors

Laminins interact with other glycoproteins like fibronectin and integrins, which bind to and signal through integrin receptors on the cell surface. These interactions are crucial for cellular attachment to the ECM and for signaling pathways that regulate gene expression and cell behavior. Moreover, laminins are associated with various physiological processes and diseases, such as renal glomerular function and Marfan syndrome, which can occur due to mutations in related glycoproteins like fibrillin. The correct option is 2) cell-surface receptors