Question

This arrangement of enzyme and DNA poses problems for the binding of the DNA helicase to the DNA substrate in the first place. What is the main issue with this arrangement?

1) The DNA helicase cannot recognize the DNA substrate
2) The DNA helicase is unable to bind to the DNA substrate
3) The DNA helicase is too large to fit in the arrangement
4) The DNA substrate is not compatible with the DNA helicase

Answer 1

The DNA helicase is unable to bind to the DNA substrate.

Step-by-step explanation:

The main issue with the arrangement of enzyme and DNA in this case is that the DNA helicase is unable to bind to the DNA substrate. The binding of the DNA helicase to the DNA substrate is essential for the separation of DNA strands during DNA replication. If the DNA helicase cannot bind to the DNA substrate, it will result in the failure of DNA replication.