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What are the connections between the components of the DNA Pol III holoenzyme?

User Zolbayar
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Final answer:

The DNA Pol III holoenzyme consists of several subunits that work together to carry out DNA synthesis. These subunits include the catalytic subunit, sliding clamp protein, clamp loader complex, and τ subunit.

Step-by-step explanation:

DNA replication involves several proteins and enzymes, including the DNA polymerase III holoenzyme. The DNA polymerase III holoenzyme consists of several subunits that work together to carry out DNA synthesis. Some of the main connections between the components of the DNA Pol III holoenzyme are:

  • The core catalytic subunit (α subunit) performs DNA synthesis.
  • The sliding clamp protein (β subunit) holds the DNA polymerase in place during replication.
  • The clamp loader complex (γ, δ, δ', and χ subunits) assists in loading the sliding clamp onto the DNA.
  • The τ subunit connects the DNA polymerase III core to the clamp loader complex and helps coordinate the activities of the other subunits.

User DeA
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